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An eccentric chemist of Eastern European lineage is on his way home from work, transporting a vial of a very potent liquid capable of juggling DNA from one being to another. The vial tucked among his groceries he waddles through his slum neighborhood rife with destitution and petty crime. He passes by a group of youths with a piece of cardboard pulled to the curb for their nightly session of phat beats and worm-like breakdancing. Momentarily entranced by the exotic scene, the doctor is bumped from behind by a careless black youth on a BMX which causes him to spill his belongings onto the side walk. The liquid too becomes freed from its container splattering lab coats and mesh tank tops respectively. The apologetic gaze of the two quickly turns to terror as they both realize THEY HAVE SWITCHED BODIES.
What ensues is a hilarious 90 minutes of slapstick antics with the two forced to fit in to the lifestyle of the other. The 'youth' learns to calculate the necessary velocity to sink basketballs from mid-court and the scientist has now resorted to rapping his theses to a hip-hop accompaniment at the annual biochemistry symposium. In their spare moments they race frantically to retrieve the ingredients for an antidote which is guarded by an insidious public authority figure who is also supported by the mafia. The two scheme a sophisticated plot to retrieve the necessary components from disparate locations of 'ethnic flavor'. Most of the situations end up with various mini-bosses drenched in marinara or their heads topped with chow mein noodles.
Their original bodies are finally restored, initially to their disbelief however the fact is confirmed when they check their manhood. The episode concludes with a heavy street session of more phat beats and 'urban gyrations'. The chemist finds a new respect for turntablism and hey, whaddya know, our young buck has a revitalized respect for homework himself!